Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines.Dysfunctional microglia also accumulate lipid droplets (LDs); however, the mechanism underlying increased LD load i
Abstract Background Sub-Saharan African (SSA) countries that currently face enormous healthcare challenges have implemented national health policies focusing on regional or international health commitments.These health commitments generally promote new healthcare financing policies (e.g., health insurance, user fee exemption and results-based finan
In this work, an anharmonic mass-in-mass system that can be employed as a nonlinear seismic metamaterial is represented as an equivalent anharmonic mass-spring system via an effective medium approach.The dispersion relation and the behavior of the effective mass as a function of the angular frequency obtained in the regime of weak anharmonicity dev
A new combined technique is developed for studying free convection of magnetohydrodynamic unsteady incompressible Baskets flow in a square cavity that partially heated from lower wall and regular cooling from lateral walls.Convection has been studied for several lengths of heat source, Hartman and the Rayleigh numbers.The local and average Nusselt
Research represents an essential component of the response to infectious disease outbreaks and to other public health emergencies, whether they are localised, of international concern, or global.Research conducted in such contexts also comes with particular ethics challenges, Face Serum the awareness of which has significantly grown following the E